Iindlela zokunyibilikisa i-HPMC ziquka: indlela yesisombululo esikhawulezileyo samanzi abandayo kunye nendlela yesisombululo esishushu, indlela yokuxuba umgubo kunye nendlela yokumanzisa i-organic solvent
Isisombululo samanzi abandayo se-HPMC siphathwa nge-glyoxal, esasazeka ngokukhawuleza emanzini abandayo. Ngeli xesha, asisosisombululo sokwenyani. Sisisombululo xa i-viscosity isanda. Isisombululo esishushu asiphathwa nge-glyoxal. Xa umthamo we-glyoxal mkhulu, uya kusasazeka ngokukhawuleza, kodwa i-viscosity iya kunyuka kancinci.
Ekubeni i-HPMC inganyibiliki emanzini ashushu, i-HPMC ingasasazeka ngokulinganayo emanzini ashushu kwinqanaba lokuqala, ize inyibilike ngokukhawuleza xa ipholile.
Iindlela ezimbini eziqhelekileyo zichazwe ngezantsi:
1) Faka umlinganiselo ofunekayo wamanzi ashushu kwisitya uze uwafudumeze ukuya kuthi ga kwi-70 ℃. I-Hydroxypropyl methylcellulose yongezwa kancinci kancinci xa ixutywa kancinci, i-HPMC yaqala ukudada phezu kwamanzi, yaza yaqala ukwenza i-slurry kancinci kancinci, eyapholiswa xa ixutywa.
2) Yongeza i-1/3 okanye i-2/3 yamanzi afunekayo kwisitya, ufudumale uye kuma-70 ℃, usasaze i-HPMC ngokwendlela ye-1) ukulungiselela i-slurry yamanzi ashushu; Emva koko yongeza amanzi abandayo aseleyo kwi-slurry yamanzi ashushu, uvuselele kwaye upholise umxube.
I-HPMC yamanzi abandayo ngokukhawuleza inokunyibilikiswa ngokongeza amanzi ngqo, kodwa ixesha lokuqala le-viscosity yimizuzu eli-1 ukuya kweli-15. Ixesha lokusebenza aliyi kudlula ixesha lokuqala.
Indlela yokuxuba umgubo: Umgubo we-HPMC usasazwa ngokupheleleyo ngokuxuba okomileyo kunye nezinye izinto zomgubo ezifanayo okanye ezingaphezulu, uze unyibilike ngamanzi. Kwimeko enjalo, i-HPMC inokunyibilika ngaphandle kokuyibeka eqokobheni.
Indlela yokumanzisa isinyibilikisi sendalo:
I-hydroxypropyl methylcellulose inokunyibilikiswa ngokuyisasaza kwi-organic solvent okanye ngokuyimanzisa nge-organic solvent, uze uyifake emanzini abandayo okanye emanzini abandayo. I-ethanol, i-ethylene glycol, njl.njl. zingasetyenziswa njenge-organic solvent.
Ixesha lokuposa: Jan-20-2022