I-8-Hydroxyquinoline (8-HQ)
Impahla: 8-Hydroxyquinoline (8-HQ) enomgangatho ophezulu
I-CAS#:148-24-3
Ifomula yeMolekyuli: C9H7NO
Ifomula yoLwakhiwo:
Ukusetyenziswa: Izixhobo zokuxuba amayeza; Izixhobo zokuxuba izibulali-zinambuzane kunye nezixhobo zokuxuba idayi
Iinkcukacha:
| Into | Umgangatho |
| Inkangeleko | Phantse imhlophe okanye imdaka kancinci i-crystalline powder okanye ii-spiculate crystals |
| Ivumba elibi | I-Phenolic |
| Isisombululo (10% kwi-alc) | Icacile ngokwenene |
| Iintsimbi ezinzima | ≤20ppm |
| Intsalela ekutshisweni | ≤0.2% |
| Intsimbi | ≤20ppm |
| Uluhlu lokunyibilika | 72-75℃ |
| I-chloride | ≤0.004% |
| I-Sulfate | ≤0.02% |
| Uvavanyo | 99-99.8% |
| 5-Hydroxyquinoline | ≤0.2 % |
Ukuchithwa
Iyanyibilika kwi-ethanol, i-acetone, i-chloroform, i-benzene kunye ne-mineral acid, ayinyibiliki emanzini.
I-8-hydroxyquinoline yi-amphoteric, inyibilika kwii-asidi eziqinileyo kunye nee-bases, i-ionized ibe yi-negative ions kwi-bases, ibotshelelwe kwi-hydrogen ions kwi-asidi, kwaye inobunyibiliko obuphantsi kwi-pH = 7.
Ukusetyenziswa okuthe ngqo
1. Njengesixhobo esiphakathi samayeza, asikuko nje kuphela izinto ezisetyenzisiweyo zokwenziwa kwe-kexieling, i-chloroiodoquinoline kunye ne-paracetamol, kodwa sikwasisixhobo esiphakathi sedayi kunye nezibulala-zinambuzane. Le mveliso iphakathi kwe-quinoline anti amoeba drugs ene-halogenated, kubandakanya i-quiniodoform, i-chloroiodoquinoline, i-diioquinoline, njl. La mayeza adlala indima yokulwa ne-amoeba ngokuthintela iintsholongwane ze-intestinal symbiotic. Ayasebenza kwi-amoeba dysentery kwaye awanampembelelo kwi-amoeba protozoa engaphandle kwamathumbu. Kuxelwe kwamanye amazwe ukuba olu hlobo lweyeza lunokubangela i-subacute spinal cord optic neuropathy, ngoko ke ivaliwe eJapan nase-United States. I-Diioquinoline ibangela esi sifo ngaphantsi kwe-chloroiodoquinoline. I-8-hydroxyquinoline ikwasisixhobo esiphakathi sedayi kunye nezibulala-zinambuzane. Ityuwa yayo ye-sulfate kunye ne-copper zizinto zokugcina ezibalaseleyo, izibulali-ntsholongwane kunye nee-anti mildew agents. Le mveliso sisalathisi se-complexometric sohlalutyo lweekhemikhali.
2. Njenge-arhente edibanisayo kunye ne-extractant yokukhupha imvula kunye nokwahlula ii-ion zesinyithi, inokunxibelelana ne-Cu+ 2, yiba+ 2, Umphathi+ 2, Ca+ 2, Sr+ 2, Ba + 2 kunye ne-Zn+ 2、Cd+2、Al+3、Ga+3、In+3、Tl+3、Yt+3、La +3、Pb+2、B+3、Sb+ 3、Cr+3、I-MoO+ 22Ubunzima be-Mn+ 2,I-Fe+ 3, CO+ 2, Ni+ 2, PD+ 2, CE+ 3, kunye nezinye ii-ion zesinyithi. Uhlalutyo lwe-organic microanalysis, olusemgangathweni wokumisela i-heterocyclic nitrogen, ukwenziwa kwezinto eziphilayo. Ikwangumxube weedayi, izibulali-zinambuzane kunye nee-quinolines ze-halogenated. Ityuwa yayo ye-sulfate kunye ne-copper zizinto zokugcina izinto ezibalaseleyo.
3. Ukongeza i-epoxy resin adhesive kunokuphucula amandla okubopha kunye nokumelana nokuguga kobushushu kwiintsimbi (ingakumbi intsimbi engatyiwayo), kwaye idosi ngokubanzi yi-0.5 ~ 3 phr. Yinto ephakathi kwe-halogenated quinoline anti amoeba drugs, kunye ne-intermediate ye-pesticides kunye ne-dyes. Ingasetyenziswa njenge-mildew inhibitor, i-industrial preservative, i-stabilizer ye-polyester resin, i-phenolic resin kunye ne-hydrogen peroxide, kwaye ikwayi-complexometric titration indicator yohlalutyo lweekhemikhali.
4. Le mveliso ayisiyo kuphela into ephakathi kwamayeza e-halogenated quinoline, kodwa ikwayiyo into ephakathi kwedayi kunye nee-pesticides. Ityuwa yayo ye-sulfate kunye ne-copper zizinto zokugcina ulusu ezibalaseleyo, izibulali-ntsholongwane kunye nee-anti-mildew agents. Umxholo ophezulu ovumelekileyo (ubuninzi beqhekeza) kwizinto zokuthambisa yi-0.3%. Iimveliso ze-sunscreen kunye neemveliso zabantwana abangaphantsi kweminyaka emi-3 ubudala (ezifana nomgubo we-talcum) azivumelekanga, kwaye "azivumelekanga kubantwana abangaphantsi kweminyaka emi-3 ubudala" kufuneka ziboniswe kwileyibhile yemveliso. Xa usebenza nesikhumba esosulelwe yibhaktiriya kunye ne-bacterial eczema, ubuninzi beqhekeza le-8-hydroxyquinoline kwi-emulsion yi-0.001% ukuya kwi-0.02%. Ikwasetyenziswa njengesibulali-ntsholongwane, isibulali-ntsholongwane kunye ne-bactericide, kwaye isiphumo sayo sokulwa nokungunda sinamandla. I-8-hydroxyquinoline potassium sulfate isetyenziswa kwikhrimu yokhathalelo lolusu kunye ne-lotion (ubunzima beqhekeza) ukusuka kwi-0.05% ukuya kwi-0.5%.