I-4-Chloro-4'-Hydroxy Benzophenone (CBP)
Impahla: 4-Chloro-4'-Hydroxy Benzophenone (CBP)
Inombolo ye-CAS: 42019-78-3
Ifomula yeMolekyuli: C13H9O2Cl
Ifomula yoLwakhiwo:
Ukusetyenziswa: i-intermediate ye-fenofibrate.
Inkcazo:
Inkangeleko: Umgubo wekristale obomvu o-orenji ukuya kwi-brick
Ilahleko xa yomiswa: ≤0.50%
Intsalela ekutshiseni: ≤0.5%
Ukungcola okukodwa: ≤0.5%
Ukungcola okupheleleyo: ≤1.5%
Ubumsulwa: ≥99.0%
Ukupakisha: 250kg/ibhegi kunye ne-25kg/idrama yefayibha
Iimpawu zefiziksikhemikhali:
Ubuninzi: 1.307 g / cm3
Iqondo lokunyibilika: 177-181 ° C
Incopho yokutsha: 100 ° C
Isalathisi sokuqaqambisa: 1.623
Imeko yokugcina: gcina kwisikhongozeli esivalwe kakuhle. Gcina kwindawo epholileyo, eyomileyo, nengena umoya kakuhle kude nezinto ezingahambelaniyo.
Izinzi: Izinzi phantsi kobushushu obuqhelekileyo kunye noxinzelelo
Isicelo esithile
Isetyenziswa ngokubanzi kwi-organic synthesis kwaye iyinxalenye ye-radiomiphene yeziyobisi ezilwa nokuzala.
Indlela yokuvelisa:
1. I-P-chlorobenzoyl chloride yalungiswa ngempendulo ye-p-chlorobenzoyl chloride ene-anisole, ilandelwa yi-hydrolysis kunye ne-demethylation.
2. Isiphumo se-p-chlorobenzoyl chloride kunye ne-phenol: nyibilikisa i-9.4g (0.1mol) ye-phenol kwi-4ml yesisombululo se-10% ye-sodium hydroxide, yongeza i-14ml (0.110mol) ye-p-chlorobenzoyl chloride ngokuwa kwi-40 ~ 45 ℃, yongeze kwimizuzu engama-30, kwaye uphendule kubushushu obufanayo kwi-1H. Pholisa kubushushu begumbi, hluza kwaye womise ukuze ufumane i-22.3g ye-phenyl p-Chlorobenzoate. Isivuno yi-96%, kwaye iqondo lokunyibilika yi-99 ~ 101 ℃.
Indlela yemveliso:
1. I-P-chlorobenzoyl chloride yalungiswa ngempendulo ye-p-chlorobenzoyl chloride ene-anisole, ilandelwa yi-hydrolysis kunye ne-demethylation.
2. Isiphumo se-p-chlorobenzoyl chloride kunye ne-phenol: nyibilikisa i-9.4g (0.1mol) ye-phenol kwi-4ml yesisombululo se-sodium hydroxide se-10%, yongeza i-14ml (0.110mol) ye-p-chlorobenzoyl chloride ngokuhla kwi-40 ~ 45℃, yongeza kwimizuzu engama-30, uze uphendule kubushushu obufanayo kangange-1H. Yipholise kubushushu begumbi, yihluze uze wome ukuze ufumane i-22.3g ye-phenyl p-Chlorobenzoate. Isivuno yi-96%, kwaye iqondo lokunyibilika yi-99 ~ 101℃.
Ingozi kwimpilo:
ibangela ukurhawuzelelwa lusu. Ibangela ukurhawuzelelwa kakhulu emehlweni. Ingabangela ukurhawuzelelwa kwendlela yokuphefumla.
Ukulumkela:
Coca kakuhle emva kotyando.
Nxiba iiglavu zokuzikhusela / impahla yokuzikhusela / iiglasi zokuzikhusela / iimaski zokuzikhusela.
Kuphephe ukuphefumla uthuli/umsi/igesi/umsi/umphunga/isitshizi.
Sebenzisa kuphela ngaphandle okanye xa umoya ungena kakuhle.
Impendulo yengozi:
Ukuba ulusu lungcolisiwe: hlamba kakuhle ngamanzi.
Xa ulusu luvutha: funa uncedo lwezonyango.
Khulula impahla engcolileyo uze uyihlambe ngaphambi kokuba uyisebenzise kwakhona
Ukuba ungena emehlweni: Hlamba ngamanzi ngononophelo imizuzu embalwa. Ukuba unxiba iilensi zoqhagamshelwano kwaye unokuzikhupha ngokulula, zikhuphe. Qhubeka nokuhlamba.
Ukuba usaziva ukurhawuzelelwa liliso: bonana nogqirha/ugqirha.
Kwimeko yokuphefumla ngengozi: mthumele umntu kwindawo enomoya omtsha kwaye ugcine ukuphefumla kwakhe kukhululekile.
Ukuba uzive ungaphilanga, fowunela iziko/ugqirha wokucoca ukungcola emzimbeni
Indawo yokugcina ekhuselekileyo:
Gcina kwindawo enomoya opholileyo. Gcina isitya sivaliwe.
Indawo yokugcina izinto kufuneka itshixwe.
Ukukhupha inkunkuma:
Lahla izinto/izikhongozeli ngokwemigaqo yendawo.
Amanyathelo oncedo lokuqala:
Ukuphefumla: ukuba uphefumle, hambisa isigulana siye emoyeni omtsha.
Ukudibana nolusu: susa impahla engcolileyo uze uhlambe ulusu kakuhle ngamanzi anesepha namanzi acocekileyo. Ukuba uziva ungaphilanga, bona ugqirha.
Ukudibana kwamehlo: hlukanisa iinkophe uze uhlambe ngamanzi aqukuqelayo okanye ityuwa eqhelekileyo. Funa uncedo lwezonyango ngoko nangoko.
Ukuginya: jika i-gurgus kwaye ungabangeli ukuhlanza. Funa uncedo lwezonyango ngoko nangoko.
Icebiso lokukhusela umhlanguli: thumela isigulana kwindawo ekhuselekileyo. Thetha nogqirha. Bonisa ugqirha okwindawo le ncwadana yobugcisa yokhuseleko lweekhemikhali.